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Post Info TOPIC: FDA approved Vraylar (cariprazine) capsules to treat schizophrenia and bipolar disorder in adults
ed11563


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FDA approved Vraylar (cariprazine) capsules to treat schizophrenia and bipolar disorder in adults
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The U.S. Food and Drug Administration today approved Vraylar (cariprazine) capsules to treat schizophrenia and bipolar disorder in adults.

Vraylar and all other FDA-approved drugs used to treat schizophrenia and bipolar disorder have a Boxed Warning alerting health care professionals about an increased risk of death associated with the use of these drugs in older people with dementia-related psychosis. Neither Vraylar nor any other drug in this class is approved to treat such patients.

The most common side effects reported by participants receiving Vraylar in the clinical trials for schizophrenia were extrapyramidal symptoms, such as tremor, slurred speech, and involuntary muscle movements. The most common side effects reported by trial participants receiving Vraylar for bipolar disorder were extrapyramidal symptoms, the urge to move (akathisia), indigestion (dyspepsia), vomiting, drowsiness (somnolence) and restlessness.

For more information, please visit: Vraylar.



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weltschmerz


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Aye, there's the rub!
It's those pesky EPSEs. They're common to all the antipsychotics, from Chlorpromazine on up, and they're a b!tch. It's easier to live with the alien messages coming out of your toaster than it is live with the spasms and cog-wheeling. And the EPSEs can become permanent
That's why there's so much non-compliance with medication.

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Lawyerlady


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weltschmerz wrote:

Aye, there's the rub!
It's those pesky EPSEs. They're common to all the antipsychotics, from Chlorpromazine on up, and they're a b!tch. It's easier to live with the alien messages coming out of your toaster than it is live with the spasms and cog-wheeling. And the EPSEs can become permanent
That's why there's so much non-compliance with medication.

 Yes.



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weltschmerz


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I'll get excited when they come out with a medication that doesn't have such severe EPSEs. The old tricyclics to treat depression and bipolar illness were also pretty terrible. The newer selective serotonin reuptake inhibitors are better, but they're useless against psychosis.
Seems like Vraylar is just another antipsychotic in the vast array of antipsychotics that patients will refuse to take.
Can't say I blame them.

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Lawyerlady


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When we see commercials and then hear all the side effects, DH and I just share our head. An anti-depressant that can cause suicidal thoughts? It's like WTH?

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My ex was heavily medicated through high school and hated it. He refused to even consider it later in life.

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Lawyerlady wrote:

When we see commercials and then hear all the side effects, DH and I just share our head. An anti-depressant that can cause suicidal thoughts? It's like WTH?

 Most of those are the extreme examples but because one or two people became suicidal the have to write that on the label.  Even if the suicidal thoughts were from another reason/source.



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Lawyerlady wrote:

When we see commercials and then hear all the side effects, DH and I just share our head. An anti-depressant that can cause suicidal thoughts? It's like WTH?

 If you and DH are sharing a head, you might need these pills . . . 



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